iovera° treatment is simple and only takes about 30 minutes

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First, a numbing agent (topical or injected) is applied to minimize discomfort during treatment. iovera° treatment is not painful.

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Then, a small probe (we call it a “Smart Tip”) is inserted into the skin.

Under the skin, a precise cold zone forms, which temporarily freezes the targeted nerve. This immediately blocks the nerve from sending pain signals to your brain for up to 90 days.

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Your doctor will repeat this process until the targeted nerve is blocked. The entire treatment takes about 30 minutes.

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A novel way to relieve pain with cold

Everyone is familiar with the idea of using cold for pain relief. But iovera° is an innovative treatment that uses cold like no other therapy. iovera° is a type of treatment known as cryoneurolysis (kri-o-nuh-rol-i-sis), or cold therapy, to achieve cryoanalgesia (kri-o-an-al-je-ze-a).

iovera° targets the nerves

The iovera° system is a handheld device that allows your doctor to target specific nerves with just the right amount of cold. This temporarily stops the nerves from sending pain signals. iovera° is precise and safe—it cannot damage surrounding tissue.

You will feel immediate relief after treatment.

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Indication

The iovera° system is used to destroy tissue during surgical procedures by applying freezing cold. It can also be used to produce lesions in peripheral nervous tissue by the application of cold to the selected site for the blocking of pain. It is also indicated for the relief of pain and symptoms associated with osteoarthritis of the knee for up to 90 days. The iovera° system is not indicated for treatment of central nervous system tissue.

When stimulation compatible components are used, the iovera° system can also facilitate target nerve location by conducting electrical nerve stimulation from a compatible 3rd party nerve stimulator.

Important Safety Information

The iovera° system should not be used in people with the following conditions:

  • Blood that thickens when patient is exposed to cold (cryoglobulinemia), blood appearing in the urine when patient is exposed to the cold (paroxysmal cold hemoglobinuria), skin rash that appears when patient is exposed to the cold (cold urticaria), narrowing of the blood vessels in the hands and feet when patient is exposed to the cold (Raynaud’s disease), and open and/or infected wounds at or near the treatment site

Patients being treated with the iovera° system (a needle-based therapy) may experience certain reactions, including, but not limited to:

  • Bruising, swelling, inflammation and/or redness, local pain and/or tenderness, and altered feeling at the site of application

Proper use of the device as described in the User Guide can help reduce or prevent the following reactions:

  • In the area(s) where you were treated: damage to the skin from being exposed to cold or heat, darkening or lightening of the skin, and dimples in the skin
  • Outside the area(s) where you were treated: muscles may not work or move normally
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Indication

The iovera° system is used to destroy tissue during surgical procedures by applying freezing cold. It can also be used to produce lesions in peripheral nervous tissue by the application of cold to the selected site for the blocking of pain.

Important Safety Information