In studies using iovera°
for knee pain, patients had:

  • Treatment process step 1 icon

    Up to 90 days of pain
    relief

  • Treatment process step 2 icon

    Improved range of motion after knee replacement surgery

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    Reduced need for opioids 72 hours after surgery

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    Immediate pain relief and less stiffness at 30 days

Beyond the knee, iovera° is also used to treat pain in the hip, shoulder, foot and ankle, spine, and more. It can also be used to treat pain related to rib fracture and mastectomy.

iovera° has been shown to provide immediate, long-lasting pain relief

See results in
OA knee pain See results in knee
replacement surgery

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Indication

iovera° applies freezing cold to peripheral nerve tissue to block and/or relieve pain for up to 90 days. It should not be used to treat central nervous system tissue.

Important safety information

The iovera° system should not be used in people with the following conditions:

  • Do not receive treatment with ioveraº if you experience hypersensitivity to cold or have open and/or infected wounds near the treatment site.
  • You may experience bruising, swelling, inflammation and/or redness, local pain and/or tenderness, and altered feeling at the site of application.
  • In treatment area(s), you may experience damage to the skin, skin darkening or lightening, and dimples in the skin.
  • You may experience a temporary loss of your ability to use your muscles normally outside of the treatment area.
  • Talk to your doctor before receiving treatment with ioveraº.
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Indication

iovera° applies freezing cold to peripheral nerve tissue to block and/or relieve pain for up to 90 days. It should not be used to treat central nervous system tissue.

Important Safety Information