PATENTED CRYOANALGESIA IN YOUR HANDS
The iovera° System
iovera° enables you to deliver cryoanalgesia to the site of pain through a patented handheld design. The extreme cold is delivered to the targeted nerve via Smart Tips. Nitrous oxide (N2O) is the cryogen used to create the extreme cold temperatures at the distal end of the Smart Tips. The iovera° system does not use nitrogen, which can deliver temperatures that cause irreversible nerve damage.
Cartridges containing liquid nitrous oxide are inserted into the Handpiece.

During each treatment cycle, the liquid nitrous oxide flows into the attached Smart Tip, where it expands into a gas. This phase change from liquid to gas causes significant cold temperatures. Nitrous oxide boils at -88oC, so the coldest temperatures that can be attained when using nitrous oxide is -88oC. Temperatures lower than -88oC cannot be reached with this cryogen.
All Smart Tips of the iovera° system are closed-end tips (needles). The nitrous oxide that flows through the needles in the Smart Tip is safely vented through the handpiece as a gas.
Note: No fluid, chemical, or drug is injected into the body during the procedure.