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The iovera° Find a Doctor program is a directory of health care providers who have attested that they are an active user of iovera° and that it is available at the affiliated facilities listed in this directory. No fees or renumeration of any kind have been or will be paid in exchange for inclusion in this directory. Inclusion of a health care provider in this directory does not indicate an endorsement, recommendation or referral by Pacira of the health care provider or any of the affiliated facilities listed. Pacira is not responsible and shall not be held liable for any harm or damage resulting from reliance on the information provided in this directory. Pacira reserves the right to remove information from this directory in the event that a health care provider no longer meets the inclusion criteria.

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Be prepared for treatment

Indication

iovera° applies freezing cold to peripheral nerve tissue to block and/or relieve pain for up to 90 days. It should not be used to treat central nervous system tissue.

Important safety information

The iovera° system should not be used in people with the following conditions:

  • Do not receive treatment with ioveraº if you experience hypersensitivity to cold or have open and/or infected wounds near the treatment site.
  • You may experience bruising, swelling, inflammation and/or redness, local pain and/or tenderness, and altered feeling at the site of application.
  • In treatment area(s), you may experience damage to the skin, skin darkening or lightening, and dimples in the skin.
  • You may experience a temporary loss of your ability to use your muscles normally outside of the treatment area.
  • Talk to your doctor before receiving treatment with ioveraº.
More +

Indication

iovera° applies freezing cold to peripheral nerve tissue to block and/or relieve pain for up to 90 days. It should not be used to treat central nervous system tissue.

Important Safety Information

Additional Information

Pacira Pharmaceuticals, Inc.

A subsidiary of Pacira Biosciences, Inc.

10410 Science Center Drive, Building A

San Diego, CA 92121 U.S.A

Legal Disclaimer

Zimmer Biomet acquired the iovera° business from Pacira BioSciences, Inc. on 31 Jul 2026, obtaining contractual agreement for the development, manufacture, and commercialization of iovera°.

During the transition period under the applicable Transition Services Agreement, Pacira remains the legal manufacturer for applicable iovera° products and retains the related regulatory responsibilities.

Zimmer Biomet acts as a contracted service provider, performing certain design, manufacturing, quality, and post-market activities under Pacira's quality system and oversight until the transition is complete.